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Literature summary for 3.4.24.69 extracted from

  • Joussain, C.; Le Coz, O.; Pichugin, A.; Marconi, P.; Lim, F.; Sicurella, M.; Salonia, A.; Montorsi, F.; Wandosell, F.; Foster, K.; Giuliano, F.; Epstein, A.L.; Aranda Munoz, A.
    Botulinum neurotoxin light chains expressed by defective herpes simplex virus type-1 vectors cleave SNARE proteins and inhibit CGRP release in rat sensory neurons (2019), Toxins, 11, E123 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.69

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
synaptosome-associated protein SNAP-25 + H2O Clostridium botulinum
-
 ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O Clostridium phage c-st
-
 ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O Clostridium botulinum ATCC 3502
-
 ?
-
 ?
Syntaxin + H2O Clostridium phage c-st
-
 ?
-
 ?
vesicle-associated membrane protein-2 + H2O Clostridium botulinum
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium botulinum P0DPI1
-
-
Clostridium botulinum P19321
-
-
Clostridium botulinum P30996
-
-
Clostridium botulinum Q00496
-
-
Clostridium botulinum ATCC 3502 P0DPI1
-
-
Clostridium phage c-st P18640
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
synaptosome-associated protein SNAP-25 + H2O
-
 Clostridium botulinum ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O
-
 Clostridium phage c-st ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O
-
 Clostridium botulinum ATCC 3502 ?
-
 ?
Syntaxin + H2O
-
 Clostridium phage c-st ?
-
 ?
vesicle-associated membrane protein-2 + H2O
-
 Clostridium botulinum ?
-
 ?

Synonyms

Synonyms Comment Organism
BoNT-A subtype Clostridium botulinum
BoNT-C subtype Clostridium phage c-st
BoNT-D subtype Clostridium botulinum
BoNT-E subtype Clostridium botulinum
BoNT-F subtype Clostridium botulinum
Botulinum neurotoxin
-
 Clostridium botulinum
Botulinum neurotoxin
-
 Clostridium phage c-st

General Information

General Information Comment Organism
physiological function the enzyme inhibit secretion of CGRP neuropeptide neurons Clostridium botulinum
physiological function the enzyme inhibit secretion of CGRP neuropeptide neurons Clostridium phage c-st